Grants

Grants for Research for Arts and Sciences Professors (GRASP), College of Liberal Arts and Sciences, Villanova University (2023) “Hitting the target: Determining how therapeutic Nrf2 activators target Keap1 C151,” PI ($25,000).

National Institutes of Health R15 (2022) “Treatment Strategy to Enhance Nrf2 Signaling in Older Adults: Combining Acute Exercise with the Phytochemical Sulforaphane,” Co-I ($74,833 to Eggler lab).

Small Research Grant, Institute for Research & Scholarship, Villanova University (2022) “From Accidental Discovery to Anticancer Treatment: Combining Two Distinct “Antioxidants” to Selectively Kill Cancer Cells,” PI ($4,957).

National Institutes of Health R15 (2021) “Cellular effects of subway air particles in human lung cells,” Co-I ($346,692).

Small Research Grant, Institute for Research & Scholarship, Villanova University  (2021) “Refining the Dose-Equivalence/Zero-Interaction (DE/ZI) method of assessing drug-drug interactions, applied to the Nrf2 cytoprotection pathway,” PI ($1,700).

National Science Foundation Grant (2020) “MRI: Acquisition of a Liquid Chromatography Tandem (QqTOF) Mass Spectrometer to Enhance Undergraduate Research and Teaching at a Primarily Undergraduate Institution,” Co-PI (one of 5) ($377,595.00). 

NovaCell/Janssen (2020) “Investigating the effects of bioprocess conditions on killer T cell growth, differentiation and function,” Co-PI (one of 3) ($35,000).

Sponsored by College of Engineering, Villanova University (2019) “Small-Molecule Nrf2 Activators as a Novel Cryoprotection Strategy for T Cell Therapies,” Co-PI (one of 2) ($25,000).

University Summer Grants Program, Villanova University (2018) “Bridging the Gap Toward Implementing Synergistic Nrf2 Activators in Chronic Disease Prevention,” PI ($12,500).

National Science Foundation Grant (2018) “MRI: Acquisition of a 500 MHz Nuclear Magnetic Resonance (NMR) Spectrometer to Enhance Undergraduate Research and Teaching at a Primarily Undergraduate Institution,” Co-PI (one of 5) ($510,990).

Villanova University NovaCell Center Grant (2018) “Boosting the ability of T cells to withstand cryopreservation-induced stress with small molecule Nrf2 activators,” Co-PI with Dr. Jens Karlsson, ($4250 of $5000 to Eggler lab).

University Summer Grants Program, Villanova University (2016) “Towards the development of therapeutics for disease prevention: Defining the importance and role of reactive oxygen species in activation of Nrf2 and its target genes by redox-cycling compounds,” PI ($12,500).

Faculty Development Grant, Villanova University (2015) PI ($1,400).

Cottrell College Science Award-Research Corporation (2014) “Activation of the Nrf2 pathway by oxidizable diphenol compounds: Elucidating the contributions of the electrophilic form and reactive oxygen species,” PI ($35,000 external, $10,000 internal).

Summer Research Fellowship/Research Support Grant, Villanova University (2013) PI ($12,500).

Phytochemical Society of North America Young Investigator Research Grant Award, sponsored by Elsevier journal Phytochemistry, (2013) “Evaluating the mechanism by which phytochemicals activate cytoprotective/disease-preventive enzymes via Nrf2,” PI ($10,000). 

National Institutes of Health R03 (2008) “Investigating Nrf2 Phosphorylation in the Mechanism of Cancer Prevention Agents” PI.